Pearson

Protein Evolution.

The tutorial will present an updated emphasis on the statistics of protein sequence comparison and protein sequence/protein structure relationships. In giving talks over the past few years, I have found that there is a surprising amount of misinformation about what is known and not known about protein evolution. The tutorial is aimed at both biologists and computer scientists, and will survey our current understanding of protein evolution,and how conclusions about evolutionary ancestry can be based on sequence and structure comparisons.